Theories and causes

Dr. Chris Pollitt is one of the most leading and groundbreaking researchers on the subject of laminitis. He made the following, not very optimistic remark about scientific research on the disease: “One-half of laminitis science is incorrect but which half?”

Theories and causes


Several types of carbohydrates (sugars or saccharides) can be distinguished: Simple sugars (monosaccharides) such as glucose (dextrose) and fructose (fruit sugar) Dual sugars (disaccharides) such as sucrose (beet sugar) Fructans such as inulin, levan and oligofructose Complex sugars (polysaccharides), such as starch…
Theories and causes


One enzyme of interest is the cartilage destroying enzyme ADAMTS-4. In the lamellae a protein is present that is degraded by this enzyme. Too much of this enzyme could lead to weakening of the lamellae and therefore weakening of the…
DefinitionTheories and causes

Hypertrichosis or hirsutism?

Human medicine distinguishes between hypertrichosis and hirsutism. Both terms refer to a condition associated with excessive hair growth. Hirsutism is characterized by excessive hair growth in those parts of the body where hair normally is absent or minimal. In humans,…
Theories and causes

PPID a hype?

A lot more horses are now diagnosed with PPID than there were ten years ago. So many more that some people label PPID as a hype. Yet this is not justified. Firstly, the clinical signs of PPID are no longer…
Theories and causes

C3 and C4 grasses and starch

Grass species can be divided into two groups: C3 grasses that thrive especially in colder climates and seasons and C4 grasses that grow well in hot, humid climates and seasons. This classification is based on the different ways photosynthesis takes place…
Theories and causes

Incretins and hyperinsulinemia

In the gastro-intestinal tract, specialized cells secrete incretins after the ingestion of food. Two important incretins are GIP and GLP-1: GIP stands for glucose-dependent insulinotropic polypeptide GLP-1 stands for glucagon-like peptide-1. These incretins are produced in the small intestine shortly after the…